SWSLHD covers seven Local Government Areas. Each LGA has its own unique population including the multiculturally diverse communities of Fairfield and Bankstown, the rapidly growing communities of Campbelltown, Liverpool and Camden and the rural towns, villages and communities of Wollondilly and Wingecarribee.

The District is among the most rapidly growing populations in NSW and projected to grow to over more than a million people in the next decade. It is also a vibrant, culturally diverse region with almost a third of its population speaking a language other than English at home.

The District covers both rural and suburban communities and manages six acute public hospitals and a range of other services to provide comprehensive healthcare for the population of south western Sydney:

These facilities and services include:

The District also operates 14 major community health centres providing prevention, early intervention and community-based treatment, palliative care and rehabilitation services.

Population Health, Oral Health, Drug Health and Mental Health services are provided at a number of facilities across the District.

Affiliated Health Services include: Karitane, Braeside Hospital and the NSW Service for the Treatment and Rehabilitation of Torture and Trauma Survivors.